West Orange Office: 375 Mt Pleasant Ave Suite 105, West Orange, NJ 07052
Phone and Fax:   Phone: 973-322-6900    Fax: 973-322-6999

Specializing in the treatment of children with endocrine disorders
Type 1 diabetes, Type 2 diabetes, Hypothyroidism, Hyperthyroidism, Graves Disease, Short Stature, Growth Hormone Deficiency, Precocious (early) puberty, Delayed Puberty, Adrenal Insufficiency, Obesity, Rickets, Osteoporosis, low Vitamin D levels, Prader-Willi Syndrome, Short stature due to small for gestational age, Hypercholesterolemia and Hyperlipidemia (High cholesterol)

The Division of Pediatric Endocrinology is located at the Saint Barnabas Pediatric Specialty Center, 375 Mt Pleasant Ave Suite 105, West Orange, NJ 07052. Our office is readily accessible from many surrounding communities in Essex, Passaic, Morris, Union, Bergen, Hudson, Middlesex, and Somerset counties.

Awards, Honors & Recognition

Specialty: Pediatric Endocrinology

Practice Contact Information:

Publications / Poster Presentations

1. Central Precocious Puberty Associated with a Dax-1 (NROB1) Mutation Causing Adrenal Hypoplasia Congenita. Brenner D, Elbashir A. Poster Presentation, Endocrine Society Annual Meeting, May 5-8, 2015, San Diego, CA

2. Optimal Hyperlipidemia Monitoring in Children and Adolescents with Type 1 Diabetes Mellitus. Allen HA, Brenner D, Reiter O. Poster Presentation, Lawson Wilkins Pediatric Endocrine Society Meeting, Honolulu, Hawaii, May 2008

3. Prospective Detection Of Hyperglycemia In Critically Ill Children Using Continuous Glucose Monitoring. Allen HF, Rake A, Roy M, Brenner D, McKiernan CA. Pediatric Critical Care Medicine. 9(2):153-158, March 2008.

4. Association Between Phone Contact And Inter-visit Glycemic Control In Type 1 Diabetic Children. Brenner D, Ben-Chaim A, Allen HF, Reiter EO. Presented at American Diabetes Association Scientific Session, Chicago, IL, June 22-24, 2007.

5. Does Increased BMI Impair Predicted Adult Height in Female Patients Treated with Depot GnRH for Precocious Puberty? Morneault E, Allen HA, Brenner D, Poster presentation, Lawson Wilkins Pediatric Endocrine Society Meeting, Toronto, Canada, May 7, 2007.

6. Birth Weight Percentiles in Obese Hyperinsulinemic and Obese Hyperandrogenemic Adolescent Females Compared to Obese Controls. Brenner D, Allen HF, Reiter EO. Poster presentation, Endocrine Society Annual Meeting, Boston, MA, June 2006.

7. Assessment of Body Composition in Girls treated for Precocious Puberty with GnRH Agonists. Brenner D, Allen HF, Reiter EO. Poster presentation, ESPE-LWPES joint meeting, Lyon, France, September 2005.

8. A randomized controlled trial of OCP vs OCP with metformin in adolescents with PCOS. Allen HF, Brenner D, Reiter, EO. Poster presentation, ESPE-LWPES joint meeting, Lyon, France, September 2005.

9. Parental Attitudes about Hypoglycemia in Type I Diabetics. Brenner D, Carey DE, Frank GR, Kreitzer P. Poster presentation, Endocrine Society Annual Meeting, San Diego, CA, June 2005.

10. Acquired Abnormalities Of The Hypothalamic-Pituitary Axis Leading To Growth Impairment. Brenner DJ, Reiter EO. Chapter, in “Clinical Pediatric Endocrinology” 5^th Edition, Blackwell Publishing, 2005 Edited by Charles Brook.

11. Immunoregulatory T Cell Population In New-onset Type I Diabetic Children Compared To That Of Normal Children. Brenner DJ, McCloskey TW, Pahwa S, Speiser PW Poster presentation, Endocrine Society Annual Meeting, New Orleans, LA, June 2004.

12. Congenital Adrenal Hyperplasia due to 21-hydroxylase Deficiency. Speiser PW, Brenner DJ. Endocrinologist. 13(4):334-340, July/August 2003.

13. Successful Computerization of a Hospital-Based Pediatric Endocrinology Practice. Brenner DJ, Carey DE, Frank GR, Fort P, Kreitzer PK, Speiser PW Poster presentation, Lawson Wilkins Pediatric Endocrine Society Meeting, Baltimore, MD, May 2002.

14. Precocious Puberty in Rubinstein-Taybi Syndrome. Brenner DJ, Speiser PW. Poster presentation, Endocrine Society Annual Meeting, Denver, CO, June, 2001.

15. Profiles of obese children presenting for metabolic evaluation. Anavian J, Brenner DJ, Fort P, Speiser PW. Journal of Pediatric Endocrinology and Metabolism 2001 Sep Oct;14(8):1145-50

Research

• Principal investigator, Macrogenics Protégé, Protégé Extension, Protégé Subcutaneous, and Protégé Encore studies, 2008 - 2012

• Principal investigator, Pfizer “Individualized, Target-Driven Treatment Of Children With Idiopathic Short Stature”, 2008 - 2012

• Principal investigator , Insmed, “Research Study Using Recombinant Human Insulin-Like Growth Factor-1/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 for Children With Noonan Syndrome”, 2006

• Principal investigator, Tercica, IGF-1 and growth hormone combined treatment study, 2008 - 2012

• Principal investigator, Tercica, “Recombinant Human Insulin-like Growth Factor-1 (rhIGF-1) treatment of pre-pubertal children with growth failure associated with primary IGF-1 Deficiency, An Open Label Multi Center, Extension Study”, 2008 - 2012

• Principal Investigator, A Multicenter, Randomized, Double-Blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Saxagliptin (BMS-477118) in Combination with Metformin IR or Metformin XR in Pediatric Patients with Type 2 Diabetes who have Inadequate Glycemic Control on Metformin Alone; Bristol- Myers Squibb, 2012 - 2013

• Principal Investigator, Colesevelam oral suspension as monotherapy or add-on to metformin therapy in pediatric subjects with type 2 diabetes mellitus; Daiichi Sankyo Pharma Solutions, 2012 - present

• Principal Investigator, An open-label, non-comparative, multicenter study on the efficacy, safety, and pharmacokinetics of triptorelin pamoate (embonate) 22.5 mg 6-month formulation in patients suffering from central (gonadotropin-dependent) precocious puberty; Debio Pharm Group, 2012 - 2014

• Principal Investigator, Natural history study of the development of type 1 diabetes; Trial Net , 2012 – present

• Sub investigator, Novo-Nordisk, “Norditropin National Registry protocol”, 2010 - present

• Sub investigator, Pfizer, “KIGS Registry for Growth Hormone Therapy”, 2010 - 2012

• Sub investigator, Eli Lilly, “GENESIS” registry , 2012 - present

• Sub investigator, Genentech “A Postmarketing Surveillance Program for Nutropin, Nutropin AQ, and Protropin”, 2010

• Principal Investigator, Versartis, VRS-317 (long-acting hGH) in Children with Growth Hormone Deficiency, 2013

• Principal Investigator, Novo Nordisk, Efficacy and safety of liraglutide in combination with metformin versus metformin monotherapy on glycaemic control in children and adolescents with type 2 diabetes, 2012 - present

Speaking Engagements

“An interesting case of short staure” Saint Barnabas Medical Center, Livingston, NJ, Feb 2015<

“What is the diagnosis? Severe Hypothyroidism.” Newark Beth Israel Medical Center, Newark, NJ, November 2013

“Treatment of Hyperlipidemia in Pediatrics” Saint Barnabas Medical Center Pediatric Nephrology Symposium, October 2013

“Cushing’s Disease in Pediatrics” Newark Beth Israel Medical Center, Newark, NJ, February 2013

“Update on the Treatment of Diabetes", Grand Rounds, Trinitas Medical Center, Elizabeth, New Jersey, July 2012

“Obesity” Saint Barnabas CME program, April 2012

“Endocrine issues in neonatology” Newark Beth Israel Medical Center, Newark, NJ, November 2011

“An interesting case of Short Stature” JFK Medical Center, Edison, NJ, July 2011

"Update on the Treatment of Diabetes", Grand Rounds, Newark Beth Israel Medical Center, Newark, New Jersey, March 2010

"Advances in the Treatment of Diabetes", Grand Rounds, Saint Barnabas Medical Center, Livingston, New Jersey, April 2009

"Endocrine Emergencies," Grand Rounds, Newark Beth Israel Medical Center, Newark, New Jersey, December 2008

“Medical Complications of Obesity” JFK Medical Center, Edison, NJ, October 16, 2008

“Costs and Benefits of EMR implementation” Lawson Wilkens Pediatric Endocrinology Society Annual Meeting, Toronto, Canada, May 6, 2007.

“The Posterior Pituitary.” Pediatric Grand Rounds, Baystate Children’s Hospital, Springfield, MA, August, 2006.

“Precocious Puberty.” Reproductive Endocrinology Grand Rounds, Baystate Medical Center, Springfield, MA April 2006.

“Computerization of the pediatric endocrinology practice” Hackensack University Medical Center, Hackensack, NJ, April 7, 2005.

“Treatment of Small for Gestational Age Infants with Growth Hormone”, Springfield, MA, March 29, 2005.

“Recognition and Treatment of Diabetic Ketoacidosis.” Pediatric Grand Rounds, Baystate Medical Center, August 31, 2004.

“Doctors on call: Pediatric Diabetes.” WGBY, Public Broadcasting Service, Springfield, MA, March 23, 2004.

“Transition from Pediatric to Adult Endocrine Care.” Adult Endocrinology Grand Rounds, Baystate Medical Center, December 30, 2003.